What is Rutin?
- Each Enteric Coated Capsule from Thera-P Complete™ contains 150 mg of Rutin, Extracted from Sophora Japonica.
- It has synergetic effects when it combined with Trypsin, Chymotrypsin and Bromelain.
- Till date, over 130 registered therapeutic medicinal preparations are containing Rutin in their formulations around the world.
Mechanism Of Action
- Rutin has demonstrated a number of pharmacological activities, including antioxidant, cytoprotective, vasoprotective, anticarcinogenic, neuroprotective and cardioprotective activities.
- The recommended dose is 100 mg - 200mg three times daily
Contraindications
- Avoid use in case of Allergy to any of the capsule components.
- Infants and Children.
- Avoid use in Pregnancy/Lactation. Consult your physician first.
Anticancer effects of Rutin on different cell lines
| Cell | Type | Benefits | Reference |
|---|---|---|---|
| HL-60 | Leukemia | Significant reduction in tumor size | Lin et al. (2012) |
| SW480 | Colon cancer | Less harmful effects on body weight and relative organ weight in mice, increased mean survival time | Alonso-Castro et al. (2013) |
| LAN-5 | Neuroblastoma | Decreased BCL2 expression and BCL2/BAX ratio along with reduction in levels of MYCN mRNA level and the secretion of TNF-α | Y.S. Chen at al. (2013) |
| CRC | Colorectal | Cell cycle arrest and/or apoptosis | Araujo et al. (2011) |
| B16F10 | Pulmonary metastasis | Reduction in the number of metastatic nodules | Martinez Conesa et al. (2005) |
Therapeutic use
For full details please read these articles from: US National Library of Medicine, National Institutes of Health website:
○ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355559/
○ https://www.ncbi.nlm.nih.gov/pmc/?term=rutin
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.