Rutoside Trihydrate (Rutin)

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What is Rutin?

  • Each Enteric Coated Capsule from Thera-P Complete™ contains 150 mg of Rutin, Extracted from Sophora Japonica.
  • It has synergetic effects when it combined with Trypsin, Chymotrypsin and Bromelain.
  • Till date, over 130 registered therapeutic medicinal preparations are containing Rutin in their formulations around the world.

Mechanism Of Action

  • Rutin has demonstrated a number of pharmacological activities, including antioxidant, cytoprotective, vasoprotective, anticarcinogenic, neuroprotective and cardioprotective activities.
  • The recommended dose is 100 mg - 200mg three times daily

Contraindications

  • Avoid use in case of Allergy to any of the capsule components.
  •  Infants and Children.
  •  Avoid use in Pregnancy/Lactation. Consult your physician first.

Anticancer effects of Rutin on different cell lines

CellTypeBenefitsReference
HL-60LeukemiaSignificant reduction in tumor sizeLin et al. (2012)
SW480Colon cancerLess harmful effects on body weight and relative organ weight in mice, increased mean survival timeAlonso-Castro et al. (2013)
LAN-5NeuroblastomaDecreased BCL2 expression and BCL2/BAX ratio along with reduction in levels of MYCN mRNA level and the secretion of TNF-αY.S. Chen at al. (2013)
CRCColorectalCell cycle arrest and/or apoptosis Araujo et al. (2011)
B16F10 Pulmonary metastasisReduction in the number of metastatic nodulesMartinez Conesa et al. (2005)

Therapeutic use

For full details please read these articles from: US National Library of Medicine, National Institutes of Health website:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355559/
https://www.ncbi.nlm.nih.gov/pmc/?term=rutin

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.